| Erreger |
1. Wahl (bis ein Antibiogramm
vorliegt!) |
Alternativen |
| Acitenobacter spezies |
 | Imipenem
|
| Ampicillin/Sulbactam |
| Meropenem |
| Aminoglykoside |
| Chinolone |
|
| Piperacillin/Tazobactam |
| Ceftazidim |
| Cotrimoxazol |
|
|
Aeromonas hydrophila
|
| Ciprofloxacin
|
| Norfloxacin |
| Tetracycline |
|
| Cotrimoxazol |
| Aminoglykoside |
|
Aktinomyzeten
|
| Ampicillin
|
|
| Tetracycline |
| Amoxicillin/Clavulansäure |
|
|
Bacillus anthracis
|
| Penicillin G
|
|
| Tetracycline |
| Erythromycin |
|
|
Bacillus spezies
|
| Clindamycin |
| Aminoglykoside |
|
| Erythromycin |
| Ciprofloxacin |
| Vancomycin |
| Meropenem |
| Imipenem |
|
|
Bacteroides fragilis
|
| Metronidazol
|
| Clindamycin
|
|
| Meropenem |
| Imipenem |
| Cefoxitin |
| Amoxicillin/Clavulansäure |
| Ampicillin/Sulbactam |
| Piperacillin/Tazobactam |
|
|
Bordetella spezies
|
| Erythromycin (Roxithromycin, Clarithromycin)
|
|
| Ampicillin |
| Amoxicillin |
| Cotrimoxazol |
|
Borrelia
burgdorferi
|
| Penicillin
|
| Doxycyclin
|
| Ceftriaxon (bei chronischem Infekt oder Neuroborreliose) |
|
| Cefuroximaxetil |
| Amoxicillin |
|
|
Branhamella (Moraxella)
catarrhalis †
|
| Amoxicillin/Clavulansäure
|
| Ampicillin/Sulbactam |
| Cotrimoxazol |
|
| Doxycyclin |
| Erythromycin |
| Cefuroximaxetil |
| Cefixim |
| Cefpodoxim |
| Cefaclor |
| Ceftibuten |
| Chinolone |
|
Brucellen
|
| Doxycyclin (+Rifampicin) |
|
| Cotrimoxazol + Gentamycin |
|
|
Burkholderia cepacia
(Pseudomonas cepacia)
|
| Ciprofloxacin
|
| Cotrimoxazol |
|
| Ceftazidim |
| Meropenem |
| mipenem |
|
|
Campylobacter spezies
|
| Erythromycin (Roxithromycin, Clarithromycin) |
|
| Tetracycline |
| Chinolone |
|
|
Chlamydia
spezies
|
| Tetracycline |
| Erythromycin (Roxithromycin, Clarithromycin) |
|
| Sulfonamide |
|
Chlamydia
pneumoniae
|
| Tetracycline
|
| Erythromycin (Roxithromycin, Clarithromycin) |
|
| Clindamycin |
|
|
Citrobacter spezies
|
| Aminoglykoside
|
| Cefotaxim |
| Ceftazidim |
| Cefepim |
| Ceftriaxon |
| Cefmenoxim |
| Aztreonam |
| Meropenem |
| Imipenem |
|
| Piperacillin/Tazobactam |
| Cefamandol |
| Chinolone |
|
|
Clostridium spezies
(siehe
Clostridium botulinum,
Clostridium perfringens,
Clostridium tetani)
|
| Penicillin G
|
|
| Tetracycline |
| Clindamycin |
| Cephalosporine |
| Meropenem |
| Imipenem |
|
|
Clostridium
difficile (pseudomembranöse
Kolitis)
|
| Vancomycin
|
| Teicoplanin
|
|
| Metronidazol |
|
|
Corynebacterium jeikeium †
|
| Vancomycin |
|
| Ciprofloxacin |
| Rifampicin |
|
|
Coxiella burnetii (Q-Fieber)
|
| Doxycyclin
|
|
| Ceftriaxon |
| Erythromycin |
|
|
Diplococcus pneumoniae
|
| Penicillin G |
|
|
|
Eikenella corrodens †
|
| Amoxicillin/Clavulansäure |
| Ampicillin/Sulbactam |
|
| Erythromycin (Roxithromycin, Clarithromycin) |
| Doxycyclin |
|
|
Enterobacter spezies †
|
| Aminoglykoside
|
| Imipenem
|
| Meropenem |
| Cefepim |
|
| Chinolone |
| Cotrimoxazol |
| Doxycyclin |
| Piperacillin/Tazobactam |
|
|
Enterokokken †
|
| Ampicillin
|
|
| Mezlocillin |
| Tetracycline |
| Piperacillin |
| Erythromycin |
|
|
Escherichia coli †
(siehe
enterohämorrhagische E. coli,
enteropathogene E. coli)
|
| Amoxicillin
|
| Ampicillin |
| Cephalosporine |
|
| Cephalosporine der neueren Generation |
| Chinolone |
|
|
Fusobakterien †
|
| Penicillin
|
|
| Metronidazol |
| Clindamycin |
|
|
Gardnerella vaginalis (Aminkolpitis)
|
| Metronidazol
|
|
| Amoxicillin |
|
Gonokokken
|
| Penicillin
|
| Ceftriaxon (Einmaldosis) |
|
| Spectinomycin |
| Erythromycin |
| Tetracycline |
| Oralcephalosporine |
| Cefoxitin |
| Cefotaxim |
| Cefmenoxim |
| Ceftazidim |
| Chinolone |
|
|
Hämophilus
influenzae
|
| lebensbedrohliche Infektion |
|
| Cefotaxim
|
| Ceftriaxon |
|
| Ampicillin |
| Amoxicillin |
| Cefotiam |
| Ceftazidim |
| Cefmenoxim |
| Cefepim |
|
| nicht lebensbedrohliche Infektion |
|
| Ampicillin
|
| Amoxicillin
|
|
| Cefaclor |
| Cefuroximaxetil |
| Cefixim |
| Cefpodoxim |
| Ceftibuten |
|
|
Helicobacter
pylori
|
| Amoxicillin-Monotherapie Clarithromycin-Monotherapie Triple-Therapie:
 | Metronidazol
|
| Amoxicillin oder Clarithromycin
|
| Protonenpumpenhemmer (z.B. Antra®)
|
|
|
| Metronidazol |
|
|
Kingella kingae †
|
| Penicillin |
| Ampicillin |
|
| Cephalosporine |
| Aminoglykoside |
| Tetracycline |
|
|
Klebsiellen †
|
| Cefotaxim |
| Cefotiam |
| Ceftazidim |
| Ceftriaxon |
| Cefmenoxim |
| Cefoperazon |
| Cefepim |
|
| Aminoglykoside |
| Chinolone |
|
|
Lactobazillen
|
| Clindamycin |
| Erythromycin |
|
| Gentamycin |
| Tobramycin |
|
Leptospiren
|
| Penicillin
|
|
| Tetracycline |
|
|
Legionella pneumophila
|
| Erythromycin (Roxithromycin, Clarithromycin) |
|
| Rifampicin |
| Ciprofloxacin (nur in Kombination mit Erythromycin) |
| Ofloxacin (nur in Kombination mit Erythromycin) |
| Cotrimoxazol |
|
|
Menigokokken
|
| Penicillin G
|
| Prophylaxe: Rifampicin
|
|
| Chloramphenicol |
| Cefotaxim |
| Ceftriaxon |
|
|
Mykoplasma
pneumoniae
|
| Erythromycin (Roxithromycin, Clarithromycin) |
|
| Tetracycline |
|
|
Nokardien
|
| Cotrimoxazol
|
| Amoxicillin/Clavulansäure |
|
| Minocyclin |
| Amikacin |
| Imipenem |
| Meropenem |
|
|
Pasteurella
multiocida
|
| Penicillin G
|
|
| Tetracycline |
| Cotrimoxazol |
|
|
Peptokokken,
Peptostreptokokken †
|
| Penicillin G
|
|
| Erythromycin |
| Clindamycin |
| Cephalosporine |
|
|
Pneumokokken
|
| Penicillin G
|
|
| Erythromycin |
| Cephalosporine |
|
|
Propionibakterien
|
| Penicilline
|
|
| Cephalosporine |
| Tetracycline |
| Clindamycin |
| Erythromycin |
|
|
Proteus
mirabilis
|
| Amoxicillin
|
| Ampicillin |
|
| Cephalosporine |
|
|
Indolpositive
Proteus
(inklusive
Morganellen)
|
| Aminoglykoside |
| Cefotaxim |
| Ceftazidim |
| Ceftriaxon |
| Cefmenoxim |
| Ceftizoxim |
| Cefepim |
| Aztreonam |
|
| Amoxicillin/Clavulansäure |
| Ampicillin/Sulbactam |
| Piperacillin |
| Cefoperazon |
| Ticarcillin/Clavulansäure |
| Chinolone |
|
|
Providencia †
|
| Cephalosporine der 3.Generation |
| Ciprofloxacin |
|
| Cotrimoxazol |
|
|
Pseudomonas
aeruginosa †
|
| Piperacillin
|
| Chinolone |
| Cefsulodin |
| Ceftazidim |
| Cefepim |
|
| Tobramycin |
| Meropenem |
|
Rickettsien
|
| Tetracycline
|
|
| Chloramphenicol Erythromycin (Roxithromycin, Clarithromycin) |
|
|
Salmonella
typhi
(siehe
Salmonellen-Nachweis)
|
| Ciprofloxacin
|
| Amoxicillin |
|
| Ofloxacin |
| Ceftriaxon |
| Chloramphenicol |
|
|
Salmonella paratyphi A, B, C
(siehe
Salmonellen-Nachweis)
|
| Ciprofloxacin
|
| Cotrimoxazol |
|
| Ofloxacin |
| Ceftriaxon |
|
| Enteritis-Salmonellen
(z.B. S. typhimurium)
(siehe
Salmonellen-Nachweis)
|
i.d.R.
keine Antibiotika-Therapie (Dauerausscheidung wird begünstigt) |
|
Serratia marcescens †
|
| Amikacin |
| Cefepim |
| Cefmenoxim |
| Ceftazidim |
| Ceftriaxon |
| Ceftizoxim |
| Aztreonam |
| Imipenem |
|
| Piperacillin/Tazobactam |
| Cefotaxim |
| Chinolone |
|
Shigellen
|
| Ciprofloxacin |
| Cotrimoxazol |
|
| Ampicillin |
| Ofloxacin |
| Ceftriaxon |
| Clindamycin |
|
|
Staphylokokken
†
|
| Flucloxacillin
|
| Clindamycin
|
| Cefamandol |
| Cefazolin |
| Cefotiam |
| Cefuroxim |
|
|
|
Staphylokokken, oxacillinresistent
|
| Vancomycin |
| Teicoplanin |
|
| Quinupristin/Dalfopristin |
| Clindamycin plus Rifampicin |
| Imipenem plus Cefotiam |
|
|
Stenotrophomonas maltophilia †
|
| Cotrimoxazol
|
|
| Chinolone |
| Minocyclin |
|
|
Streptokokken (anaerob + aerob)
|
| Penicillin G
|
|
| Erythromycin (Roxithromycin, Clarithromycin) |
| Tetracycline |
| Clindamycin |
| Cephalosporine |
|
|
Toxoplasma gondii
|
| Pyramethamin + Sulfadiazin (CAVE:
Gravidität) Spiramycin |
|
|
|
Ureaplasma
|
| Doxycyclin
|
|
| Erythromycin (Roxithromycin, Clarithromycin) |
|
|
Vibrionen
(siehe
Vibrionen, Cholera-,
Vibrionen, Non-Cholera-)
|
| Tetracycline
|
| Cotrimoxazol
|
|
| Chinolone |
|
|
Yersinia enterocolitica
|
| Ciprofloxacin
|
|
| Cotrimoxazol |
| Doxycyclin |
|
| Yersinia
pseudotuberculosis |
| Tetracycline
|
|
| Ampicillin |
| Ciprofloxacin |
|
